Using partial volume information significantly improved the accuracy of the thickness estimation on synthetic
phantoms, and improved reproducibility on real data. Significant differences in the hippocampus and temporal lobe between healthy controls (NC), mild cognitive impaired (MCI) and Alzheimer’s disease (AD) patients were found on clinical data from the ADNI database. We compared our method in terms of precision, computational speed and statistical power against the Eulerian approach. With a slight increase in computation time, VS-4718 mouse accuracy and precision were greatly improved. Power analysis demonstrated the ability of our method to yield statistically significant results when comparing AD and NC. Overall, with our method the number of samples is reduced by 25% to find significant differences between the two groups. Crown Copyright (C) 2009 Published by Elsevier B.V. All rights reserved.”
“The purpose of this study was to evaluate the light intensity output of quartz-tungsten-halogen Y27632 (QTH) and light emitting diode (LED) curing devices located at governmental health institutions in Riyadh, Saudi Arabia.\n\nEight governmental institutions were involved in the study. The total number of evaluated curing devices was 210 (120 were QTH
and 90 were LED). The reading of the light intensity output for each curing unit was achieved using a digital spectrometer; (Model USB4000 Spectrometer, Ocean AZD8055 Optics Inc, Dunedin, FL, USA). The reading procedure was performed by a single investigator; any recording of light intensity below 300 mW/cm(2)
was considered unsatisfactory.\n\nThe result found that the recorded mean values of light intensity output for QTH and LED devices were 260 mW/cm2 and 598 mW/cm(2), respectively. The percentage of QTH devices and LED devices considered unsatisfactory was 67.5% and 15.6%, respectively. Overall, the regular assessment of light curing devices using light meters is recommended to assure adequate output for clinical use.”
“Within the framework of the dielectric continuum (DC) model, the optical phonon modes and electron-optical-phonon interaction in hemispherical quantum dot are investigated. The proper eigenfunctions for longitudinal optical (LO) and interface optical (IO) phonon modes are constructed. After having quantized the eigenmodes, we derive the Hamiltonian operators describing the LO and IO phonon modes as well as the corresponding Frohlich electron-phonon interaction. The dispersion relation of IO phonon modes is size independent. The potential applications of these results are also discussed. (C) 2011 Elsevier Ltd. All rights reserved.”
“MicroRNAs (miRNAs) regulate many key cancer-relevant pathways and may themselves possess oncogenic or tumor-suppressor functions. Consequently, miRNA dysregulation has been shown to be a prominent feature in many human cancers.