The other three AtNAP1 genes are ubiquitously expressed in plants and the AtNAP1;3 protein is detected as the major isoform in seedlings. We show that disruption of the AtNAP1-group genes does not affect normal plant growth under our laboratory conditions. Interestingly, two allelic triple mutants, Atnap1;1-1 Atnap1;2-1 Atnap1;3-1 and Atnap1;1-1 Atnap1;2-1 Atnap1;3-2, exhibit perturbed genome transcription, and show hypersensitivity to DNA damage caused by UV-C irradiation. We show that AtNAP1;3 binds chromatin, with selleck products enrichment at some genes involved in the nucleotide excision repair (NER) pathway, and that the expression of these genes is downregulated in the

triple mutants. Taken together, our results highlight conserved and isoform-specific properties of AtNAP1 proteins, and unravel their function in the NER pathway of DNA damage repair.”
“Cellulose nanocomposites containing high contents of Fe3O4 nanoparticles. were Successfully prepared with regenerated cellulose films as a matrix and mixture solutions of Fe2+/Fe3+ as precursors. The structure and properties of the magnetic nanocomposite films were NVP-AUY922 ic50 investigated with X-ray diffraction, scanning electron microscopy, transmission electron microscopy, thermogravmetric analysis, and vibrating sample magnetometry. Fe3O4 nanoparticles as prepared were irregular spheres and were homogeneously dispersed in the cellulose matrix. With an increase

in the concentration of precursors from 0.2 to 1.0 mol/L, the content of Fe3O4 nanoparticles in the dried nanocomposites increased from 12 to 39 wt %, and the particle diameter increased from 32 to 64 nm. The Cellulose nanocomposite films demonstrated superparamagnetic behavior, and their saturation magnetizations were in the range 4.2-21.2 emu/g, which were related to the increase in Fe3O4 nanoparticle content. With increasing nanophase content, the nanocomposite films displayed significantly anisotropic magnetic properties in the parallel and perpendicular

directions. This study provided a green and facile method for the preparation of biobased nanocomposite films with high nanophase content and excellent magnetic properties. (c) 2008 Wiley Periodicals, Inc. J Appl Polym Sci 111: 2477-2484, 2009″
“Background: Lateral tibiofemoral articular geometry may play a role in the this website development of non-contact anterior cruciate ligament (ACL) injuries. We hypothesized that athletes who had sustained an ACL injury would demonstrate more highly convex articular surfaces in the lateral compartment of the knee compared with activity-matched athletes who had not sustained an ACL injury, and that women would demonstrate greater absolute and relative convexity of these articular surfaces than men.

Methods: One hundred and twelve athletes with a non-contact. ACL injury and sixty-one activity-matched athletes without an ACL injury were studied.