\n\nResults:\n\nInterferon-beta showed a dose-dependent inhibitory effect on all serotypes. EC(50) CBL0137 supplier of interferon-beta ranged between 211 and 843 IU/mL. A similar tendency was observed with interferon-gamma. EC(50) of interferon-gamma ranged between 133 and 9130 IU/mL. Among the serotypes, interferon-gamma exhibited the greatest inhibitory effect on AdV37. In contrast, AdV4 showed the lowest sensitivity to interferon-gamma. Statistically significant

dose dependency for both interferon-beta and interferon-gamma was observed in several serotypes.\n\nConclusions:\n\nThese results suggest that both interferon-beta and interferon-gamma have anti-adenoviral activity in vitro. Interferons have the potential to be used for local treatment of adenoviral keratoconjunctivitis, although further evaluation in animal models and clinical trials is necessary.”
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series of porous pillared-zirconium phosphates functionalized with methyl, ethyl, propyl and phenyl groups were prepared and characterized by SEM, Si-29 MAS NMR, TG and N-2 adsorption. Their total surface acidity and accessible one were measured by potentiometric titration of n-butylamine and liquid phase 2,6-di-tert-butyl-pyridine adsorption, respectively. The catalytic behaviors of these hybrid materials for alkylation of hydroquinone and esterification of lauric acid were compared. Not the total acid sites but the accessible ones play a crucial role in both reactions of alkylation and esterification. The accession for acid sites can IWR-1-endo be enhanced by the introduction of alkyl/aryl groups, due to the improved hydrophobicity of the surface. (C) 2013 Elsevier B.V. All rights reserved.”
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mating type (-)-specific gene of the alpha-box and the mating type (+)-specific gene of the high-mobility group (HMG) DNA-binding this website domain were confirmed in zoophilic dematophytes of Arthroderma simii and A. vanbreuseghemii. The sequence of the alpha-box gene was 1,375 bp, containing 2 exons (from 172 to 463 bp and from 513 to 1,375 bp) in the A. simii (-) mating type strain and 1,380 bp, containing 2 exons (from 177 to 468 bp and from 518 to 1,380 bp) in the A. vanbreuseghemii (-) mating type strain. The sequence of the HMG gene was 1,871 bp, containing 2 exons (from 181 to 362 bp and from 426 to 1,440 bp, coding a protein of 398 amino acids) in the A. simii (+) mating type strain and 1,811 bp containing 2 exons (from 158 to 339 bp and from 403 to 1,381 bp, coding a protein of 386 amino acids) in the A. vanbreuseghemii (+) mating type strain. Of 15 animal isolates and 72 human isolates examined, the alpha-box gene was detected in five of the animal isolates and in none of the human isolates, while the HMG gene was detected in the other 10 of the animal isolates and in all of the human isolates.