massiliense” isolates Isolates Spacer1 Spacer2 Spacer3 Spacer4 Spacer5 Spacer6 Selleck Stattic Spacer7 Spacer8 Genotype M.abscessus_ ATCC19977_CIP104536T 1 1 1 1 1 1 1 1 1

M.abscessus_ DSMZ44567 2 1 2 2 2 1 2 1 2 P1 2 1 2 2 2 1 2 1 2 P2.1 1 2 1 3 1 1 2 2 3 P2.2 1 2 1 3 1 1 2 2 3 P2.3 1 1 1 1 1 1 1 1 1 P2.4 1 1 1 1 1 1 1 1 1 P2.5 1 1 1 1 1 1 1 1 1 P2.6 1 1 1 1 1 1 1 1 1 P3.1 3 1 2 1 1 1 2 1 4 P3.2 3 1 2 1 1 1 2 1 4 P4 1 1 1 1 1 1 1 2 5 P5 1 1 1 1 3 1 2 1 6 P6 1 1 1 1 1 1 1 1 1 P7 4 1 2 4 4 1 2 1 7 P8 4 1 2 4 4 1 3 1 8 M.abscessus_3A-0930-R_3A_0930_R 1 1 1 1 1 1 1 1 1 M.abscessus_3A-0930-S_3A_0930_S 1 1 1 1 1 1 1 1 1 M.abscessus_3A-0122-S_3A_0122_S 1 1 1 1 1 1 1 1 1 M.abscessus_3A-0731_3A_0731 Vactosertib 1 1 1 1 1 1 1 1 1 M.abscessus_3A-0122-R_3A_0122_R 1 1 1 1 1

1 1 1 1 M.abscessus_3A-0119-R_3A_0119_R 1 1 1 1 1 1 1 1 1 M.abscessus_6G-0728-R_M6G_0728_R 1 1 1 1 1 1 1 1 1 M.abscessus_6G-0212_M6G_0212 1 1 1 1 1 1 1 1 1 M.abscessus MDV3100 concentration _6G-1108_6G_1108 1 1 1 1 1 1 1 1 1 M.abscessus _6G-0728-S_6G_0728_S 1 1 1 1 1 1 1 1 1 M.abscessus_6G-0125-R_6G_0125_R 1 1 1 1 1 1 1 1 1 M.abscessus _6G-0125-S_6G_0125_S 1 1 1 1 1 1 1 1 1 M.abscessus_4S-0116-S_4S_0116_S 5 1 2 5 5 2 2 2 9 M.abscessus_4S-0116-R_4S_0116_R 5 1 2 5 5 2 2 2 9 M.abscessus_4S-0206_M4S_0206 5 1 2 5 5 2 2 2 9 M.abscessus_4S-0726-RB_4S_0726_RB 5 1 2 5 5 2 2 2 9 M.abscessus_4S-0303_4S_0303 5 1 2 5 5 2 2 2 9 M.abscessus_4S-0726-RA_4S_0726_RA 5 1 2 5 5 2 2 2 9 M.abscessus_M93 3 1 2 6 6 1 2 3 10 M.abscessus_M94 2 1 2 2 7 1 4 2 11 M.abscessus_M152 2 1 2 7 7 1 2 3 12 M.bolletti_ www.selleck.co.jp/products/CAL-101.html CIP108541T 6 3 3 3 8 1 5 2 13 P9 6 3 3 3 8 1 5 2 13 P10 7 4 1 3 8 1 2 2 14 M.abscessus_M24 8 3 4 8 8 1 2 2 15 M.massilliense_ CIP108297T 5 5 5 9 9 1 6 3 16 P11 5 5 5 9 9 1 6 3 16 M.massiliense _2B-0912-S_2B_0912_S 9 5 6 10 10 2 7 3 17 M.massiliense_2B-030_ M2B_0307 9 5 6 10 10 2 7 3 17 M.massiliense_2B-0912-R_2B_0912_R 9 5 6 10 10 2 7 3 17 M.massiliense_2B-0626_M2B_0626 9 5 6 10 10 2 7 3 17 M.massiliense_2B-1231_M2B_1231 9 5 6 10 10 2 7 3 17 M.massiliense_2B-0107_M2B_0107 9 5 6 10 10 2 7 3 17 M.massiliense _1S-154-0310_M1S_154_0310 9 5 6 10 10 2 7 3 17 M.massiliense_1S-152-0914_M1S_152_0914 9 5 6 10 10 2 7 3 17 M.massiliense_1S-153-0915_M1S_153_0915

9 5 6 10 10 2 7 3 17 M.massiliense_1S-151-0930_M1S_151_0930 9 5 6 10 10 2 7 3 17 M.massiliense _M18 9 5 6 10 10 2 7 3 17 M.abscessus_M159 9 6 6 9 10 3 7 4 18 M.abscessus_47J26 9 5 6 6 11 4 7 3 19 M.abscessus_M172 10 7 2 9 12 3 8 5 20 M.abscessus_M154 10 7 2 9 12 3 8 5 20 M.abscessus_5S-1215_5S_1215 11 5 2 6 13 2 6 2 21 M.abscessus_5S-1212_5S_1212 11 5 2 6 13 2 6 2 21 M.abscessus_5S-0817_5S_0817 11 5 2 6 13 2 6 2 21 M.abscessus_5S-0708_5S_0708 11 5 2 6 13 2 6 2 21 M.abscessus_5S-0422_5S_0422 11 5 2 6 13 2 6 2 21 M.abscessus_5S-0304_5S_0304 11 5 2 6 13 2 6 2 21 M.abscessus_5S-0421_5S_0421 11 5 2 6 13 2 6 2 21 M.abscessus_M156 10 7 2 11 12 3 9 5 22 M.abscessus_M148 10 7 2 11 12 3 9 5 23 M.abscessus_M139 10 5 2 11 14 3 10 3 24 DI 0.8295 0.6228 0.6969 0.