For some reason, our Ydler patient is failing to make the appropriate display. As a result, the parents attribute the poor performance to undermotivation,

and mistakenly think that the child is on the ascending limb of the curve, and so they keep on pushing, which drives the child further down the descending limb, which causes the parents to push even harder, which drives the child even further down the descending limb, and so on. The Yerkes-Dodson law Inhibitors,research,lifescience,medical has been criticized TGF-beta cancer because it assumes a unitary variable of arousal.68 However, it has been supported independently and, I think, unknowingly, by Hans Selye’s work on stress. Selye related strain to stressor,69 and found a U-shaped curve, so that too little stress caused strain, a middling amount caused less strain, and too much stress caused more strain. If we identify Selye’s strain as negative performance, Inhibitors,research,lifescience,medical and Selye’s stress as motivation, then Selye’s curve is the Yerkes-Dodson curve upside down. Social sharing of nonsocial anxiety Social anxiety, caused by fellow group members, is usually a solitary thing, endured by an individual bullied by a dominant, or by a scapegoat, punished by the group. But, anxiety to nonsocial sources of harm is often shared with other

group members, and so becomes a social experience, modulated by social customs. In some cases, the group comes together to reduce anxiety, as when chimpanzees cuddle each Inhibitors,research,lifescience,medical other when presented with a stuffed leopard, and so presumably revive the safety sensations of the child being cuddled by its mother; in other cases, the group allocates to an individual the responsibility for sensing danger, allowing the remainder of the group Inhibitors,research,lifescience,medical to carry out foraging and other activities free from anxiety. Alarm calls The alarm calls given by an allocated “sentry” are specializations of calls given by ordinary individuals in the group: “In 1967, T. T. Struhsaker reported that East African vervet monkeys gave different-sounding alarm calls to at least three different, predators: leopards, eagles and snakes [...] and, in play-back Inhibitors,research,lifescience,medical experiments of taperecorded

tuclazepam alarm calls [...] monkeys responded to playback of leopard alarm calls by running into trees, to eagle alarms by looking up in the air or running into bushes, and to snake alarms by looking down in the grass around them.“70 Vervets were later shown to have, in addition to the above, specific alarm calls eliciting specific responses to baboons, small carnivores, and unfamiliar humans.71 Other monkey species also have specific alarm calls, but, apes apparently do not, and human alarm calls would appear to be as nonspecific as apes, perhaps because apes and humans are under lesser prédation pressure than monkeys. Giving an alarm call is clearly a disadvantage to the individual who gives it, and the adaptive advantage accrues to close kin, and how this might evolve has been a concern of evolutionary biology.