01). Our data demonstrated that OEA and PSN632408 can stimulate beta-cell replication in vitro and in vivo and improve islet graft function. Targeting GPR119 is a novel therapeutic approach to increase beta-cell mass and to improve islet graft function by stimulating beta-cell replication.”
“The testing of the common mode transfer characteristics of Ethernet transformers with (and

without) inductive chokes is presented. The experimental results are compared selleck with analytical models of common mode transfer functions of Ethernet transformers. The theory and experiment data are found to be in good agreement. (C) 2011 American Institute of Physics. [doi:10.1063/1.3536665]“
“Purpose: To evaluate the feasibility of MR imaging to depict the in vivo recruitment of superparamagnetic iron oxide (SPIO)labeled macrophages and to aid diagnosis of graft rejection in kidney transplantation.

Materials and Methods: This study was approved by the institution’s committee on animal research. Eighteen male Lewis rats received a kidney transplant; 12 had an F344 rat donor and six had a Lewis rat donor. Peritoneal macrophages were harvested from thioglycollate-treated

Lewis rats, cultured, and labeled with SPIO. After resuspension of macrophages in a concentration of 1 x 10(7) cells per milliliter of Hanks balanced salt solution, 5 x 10(6) of SPIO-labeled macrophages was administered through the tail vein 2 or 5 days after transplantation in each group. The transplanted kidneys were imaged on a 4.7-T MR imager 24 hours after 3-MA ic50 macrophage administration. The Wilcoxon signed rank test was performed for evaluating the differences between the relative signal intensity (SI) before and after SPIO-labeled macrophage administration.

Results: A low-SI zone was predominantly noted in the medulla of the transplanted kidneys, and the relative SI decreased significantly from 1.40 to 0.53 (P < .001) in the allogeneic transplants following SPIO-labeled macrophage administration 5 days after the allogeneic transplantation. In the syngeneic group, the lower-SI zone was not noted in the grafts. At histopathologic

examination, the lower-SI zone corresponded to the distribution https://www.selleckchem.com/products/BMS-777607.html of the SPIO-labeled macrophages.

Conclusion: This study demonstrates that the homing of intravenously administered SPIO-labeled macrophages can be monitored in the allograft rejection model on in vivo MR images. (C) RSNA, 2010″
“Toroidal 32- and 64-turn transformers with a unity turn ratio and a silicon dioxide core material were fabricated and tested. The resulting differential mode transfer relation is analyzed with infinite and 100 Omega resistive loads. The best performance is found for a 32-turn transformer with a 100 Omega load, having a relatively flat transfer relation in the frequency range of 10-40 MHz. (C) 2011 American Institute of Physics. [doi:10.1063/1.