aureus strains. With an MBC50 of 16 μg/mL, the protein was bactericidal against every S. aureus strain tested. P128 time-kill kinetics were determined at MIC and higher concentrations on select isolates, and P128 was found to rapidly reduce cell numbers by 99.99%. To develop P128 as a treatment to eliminate human nasal carriage, P128 was formulated as a hydrogel and tested on nasal Staphylococci recovered from healthy people. The protein was able to kill S. aureus https://www.selleckchem.com/products/arn-509.html under conditions representing physiological conditions. Taken together, our findings demonstrate that P128 exhibits excellent antistaphylococcal properties

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